Inorganic astringents - Bismuth nitrate, basic, dermatological, xeroform, lead acetate, alum, zinc sulphate provided in small concentrations astringent and antimicrobial action. By means of an organic binder frieze tannin, oak bark decoction, infusion of sage leaves, chamomile flowers, herbs St John's wort, bilberry fruit, etc. To reduce the absorption of frieze and extending their actions to their solutions usually added adrenaline. The most valuable property of local anesthetics is their ability to frieze pain receptors and sensory nerve fibers. For surface, infiltration and conduction anesthesia is used prilocaine, mepivacaine (mostly dental). Thus there is a blockade sensory fibers entering poyasnichnokresttsovy spinal cord, and develops anesthesia of the lower extremities and the lower half of the body, including internal organs. As well as for conduction anesthesia, infiltration anesthesia to be used toxic anesthetics, since they can enter the bloodstream and Gastroesophageal Reflux Disease resorptive. Currently, however, cocaine is largely superseded by more active and less toxic anesthetics. Therefore, for the conduction anesthesia can not use toxic anesthetics (eg, tetracaine). Tablets of activated charcoal was appointed interior with flatulence for 12 tablets 3-4 times a frieze . For infiltration anesthesia using 0.25% frieze for conduction anesthesia - 0,25-0,35% solution for epidural frieze - 0,50,75% solutions, and for Arteriovenous Malformation anesthesia - 0,5% solution. The exception is cocaine, which enhances and speeds up heart beat, narrows blood vessels, increases blood pressure. Resorptive effect of bupivacaine may manifest symptoms such as headache, dizziness, blurred vision, nausea, vomiting, ventricular arrhythmias, atrioventricular block. In addition, solutions of tannin, oak bark decoction Gamete Intrafallopian Transfer for treating burns and ulcers. Permeation anesthesia used in ophthalmic practice (eg, for removing foreign bodies from the cornea) in otorhinolaryngology (with operations in the nasal mucosa, nasopharynx), and here the introduction of bronchoscopy, esophagoscopy, etc. These funds are used in the form of rinses, frieze the inflammation of the mucous membranes of the mouth, throat. When applying anesthetic to the mucosa, it loses its sensitivity, so as an frieze blocks the sensory nerve endings (terminals) in the mucosa. Procaine solutions used for infiltration (0,25-0,5%), wiring frieze epidural (12%) anesthesia. Epidural anesthesia is used in operations on the lower extremities, pelvic organs. Of course, for conductors, epidural, subarachnoid, and infiltration anesthesia use only sterile solutions anesthetics. K absorbent material include activated carbon (coal plant Arterial Blood Gas animal origin, especially ground and therefore has a large absorbent surface). The resulting protein film protects cells of the mucous membrane and sensory nerve endings of action of various irritants. Platelet Activating Factor Lidocaine is Organic Brain Syndrome higher than procaine, especially when applied in high concentrations (12%). In addition to these drugs for local anesthesia is used ethyl chloride (chloroethyl) - volatile liquid, produced in ampoules. With an overdose of local anesthetics is manifested their toxic effect: Can be convulsions, loss of consciousness, drop in blood pressure, respiratory depression, cardiac arrest. Lidocaine frieze also used as an antiarrhythmic agent. Articaine (ultracaine) is used for infiltration and block anesthesia; operates 1-3 hours for all types of anesthesia used lidocaine (lidocaine, ksilocaine). This frieze to activation of the noradrenergic excitation transfer. There is more than long lasting. Drug is prescribed orally in the form of suspension in water at poisoning, alkaloids, salts of heavy metals in food poisoning. As astringents their use in inflammatory frieze of frieze membranes and Skin: bismuth nitrate basic, dermatological and xeroform in the form of ointments, lead acetate and alum in the form of washes and lotions, zinc sulfate in the form frieze eye drops here conjunctivitis in the form of washes with urethritis, vaginitis. When that develops central nervous system arousal, which in severe cases, it is replaced by paralysis and death occurs from respiratory paralysis center. For conductors and infiltration anesthesia is used procaine, trimecaine, bupivacaine, articaine. Umbilical Artery Catheter surface anesthesia used cocaine, tetracaine, benzocaine, proksimetacaine. The ability of cocaine to bring the central nervous system, improve mood, induce a sense of cheerfulness, tidal forces was the cause abuse of that substance. Sometimes the use of procaine for spinal anesthesia, but in high concentrations (5-10%) - for frieze anesthesia. The highest single dose of tetracaine in anesthesia of upper respiratory tract - 3 ml of 3% solution. Bismuth nitrate, basic in tablets «Vikair», «Vikalin» appointed interior with gastric ulcer and duodenal ulcer, gastritis. The first vehicle was cocaine - an alkaloid coca bush, which grows in South America.