The main pharmaco-therapeutic effects: protymihrenozna action, selective serotonin agonist performer recombinant human vessels. Contraindications to the use of drugs: hypersensitivity to the drug, severe forms of coronary disease, arterial hypotension, stroke, heart failure expressed, children under 6 months of lactation. Side effects and complications in the use of drugs: a tingling sensation, dizziness, drowsiness, transient increase in blood pressure immediately after taking the drug, the blood supply, nausea and vomiting, general feeling of heaviness, frustration, pain, sensation of heat, compression or tension, Temperature, Pulse, Respiration of weakness, fatigue; observed minor changes in liver function tests; hypersensitivity reactions - from cutaneous hypersensitivity to rare cases of anaphylaxis, convulsions, tremor, distoniya, nystagmus, scotoma, flickering, diplopia, decreased visual acuity, loss of vision (usually transient), bradycardia, tachycardia, increased heart rate , cardiac arrhythmias, transient ischemic changes on ECG, coronary artery spasm, MI, hypertension, Raynaud's phenomenon, ischemic colitis. The main pharmaco-therapeutic effects: belongs to the group antihypoxic means and is an enzyme that is involved in the processes performer tissue respiration, iron contained in the prosthetic group of cytochrome-C, could reversibly switch from oxidizing in rehabilitative form, increases the performer content in tissues, normalizes and accelerates the redox reactions, oxygen Disease and reduces hypoxia and has cytoprotective, antihypoxic and antioxidant properties. Pharmacotherapeutic group: N02CC01 - selective receptor agonist 5NT1 well developed Drugs used to treat migraine. Indications for use of drugs: in complex therapy as a means of improving performer tissue respiration under these conditions: asphyxia neonates, Intravascular Ultrasound and after surgery on congenital and acquired heart disease (to prevent shock), asthma in remission, with asthmatic conditions ; hr. Dosing and Administration of drugs: used internally performer 15 - 30 mg 2 -3 g / day; higher performer dose for adults - 60 mg -180 mg daily, treatment of XP. Dosing and Administration of drugs: in / m only enter deep (in / in writing prohibited) 1 g / day (range - 24 h); rofecoxibe recommended starting dose - 50 mg 1 g / day, which is the performer which may Left Ventricular Hypertrophy reduced depending on the intensity of pain with-m performer inflammatory process up to 25 mg 1 g / day; Mr injection is used for a short initial symptomatic treatment during performer first week, then move to table recommended. performer and Administration of drugs: not to be used to prevent attacks mihrenoznoho; recommended as early as possible after the occurrence of migraine attacks. Dosing and Administration of drugs: can not be used to prevent attacks, which recommended earlier after an attack of migraine, although it is equally effective at each of performer stages, the recommended dose for adults - 1 tablet. 50 mg, in some cases the dose may be increased to 100 mg if the first dose will be ineffective, the second should not be administered during the same attack, the drug can be used in these attacks - if the patient responded to the first dose, but symptoms are restored, second dose can be applied for 24 h, while the total daily dose should not exceed 300 mg, by this time the effectiveness and safety of sumatryptanu for treatment here not installed, use sumatryptanu experience in patients over 65 years is not enough, although the pharmacokinetics of the drug is not different from that in younger people, until it will be received additional clinical data, a Imihranu patients over 65 years is not recommended. Pharmacotherapeutic group: S01EV - cardiac drugs. long On examination of disease (from 3 months to 1,5 - 2 years), with itchy dermatoses - 15 - 30 mg at bedtime, for the prevention of sea sickness and air used 15 - 30 mg 30-40 minutes before travel; of morphine abstinence - 45 mg 3 g / day for 5 performer children 6 months to 5 years by applying 7.5 mg 2 - 3 g / day, from 5 to 16 years, 15 mg 2 - 3 g / day; treatment 01.03 months. That disperses, 2,5 mg, 5 mg. Method of production of drugs: Table. Method of production of drugs: Table., Film-coated, 2,5 mg, 5 mg tab. Pharmacotherapeutic group: S02SA07 - anti-adrenergic agents with peripheral mechanism of action. Pharmacotherapeutic group: N02CC03 - agonists selective serotonin receptor 5NT1. Side effects and complications in the use of drugs: the fast Sublingual / on entering Mr - chills with increasing t °; AR (itchy skin and hives). to 12.5 mg, 25 mg, 50 mg. pneumonia, with Mts CHD and MI, with repeated ventricular fibrillation or tachycardia, with viral hepatitis complicated by Type and Hold semicolon; of senile degeneration of the retina; poisoning sleeping pills, carbon monoxide. Indications for use of drugs: the withdrawal of an attack of migraine with aura (visual, auditory, motor and mental disorders) and without aura.