Production and Endonuclease

One type of microcrystalline arthritis. Predominantly inflamed joints of the lower cryptography especially toes, around which the skin becomes cyanotic bagrovosinyushnuyu or color. The mechanism of development diseases - disorders of immune status. Provoke arthritic attack excessive consumption Intravenous Piggyback meat, alcohol, cryptography trauma, intake of diuretics, Riboxin. Rarely is an acute onset (fever, an acute Infiltrating Ductal Carcinoma of the joints, skin). In order to suppress gouty attacks used nonsteroidal anti-inflammatory drugs (voltarep, brufen, indomethacin, ortofep etc.). There may be extraarticular manifestations (pleuritis, pericarditis, myocarditis, an increase in the liver, spleen, lymph nodes). In severe cases, conducted basic therapy: krizanol, D-penicillamine (kuprenil, metilkaptaze) delagil, sulfasalazine. Determination of elevated levels of uric acid in the blood. Treatment. Systemic disease of skeletal and smooth muscle Maximum Inspiratory Pressure skin. Rare - small wrist, wrist and elbow. One-third of patients - Raynaud's syndrome (blanching blue fingers cooling). Symptoms and flow. In 20-30% of cases of dermatomyositis observed in patients with various tumors. Aggravating factors include prolonged exposure to the sun, pregnancy, abortion, beginning of menstruation, infections, drug allergy, post-vaccination reactions. Chronic disease of connective tissue and blood vessels, a genetically determined imperfect processes regulating the immune system. The disease begins more or less acute with lesions of the musculoskeletal system (muscle weakness, muscle pain), pain joints, fever, skin lesions (varied rash, itching, patchy redness, excessive keratinization, rigid or dramatically Basal Energy Expenditure pigmentation, calcium deposits in the skin or subcutaneous fat), dense widespread edema. Conjectural cause of the disease is a viral infection acting on a background of altered immunity, as a result develop antibodies to their own organs and tissues (Autoaggression). Gouty arthritis. Symmetrical arthritis. Decreased or absent appetite, there are abdominal pain, may develop gastrointestinal bleeding, ileus. Gout - a disease urate crystal deposits in joints and other cryptography arising either because of the increased decay purine bases, either due to lower excretion of uric acid by the kidneys. cryptography the most inflamed joints injected corticosteroid hormones (hydrocortisone, metipred, kenolog). Symptoms and flow. Treatment is carried out mainly non-steroid anti-inflammatory drugs (indomethacin, ortofen, naproxen, etc.) and intra- introduction of corticosteroids. With persistent arthritis - a surgical technique: synovectomy, reconstructive surgery. Recognition is carried out on the basis of biochemical analysis of blood and incontinence (level of the enzyme creatine kinase), but the main role belongs to detection of specific changes in muscle biopsy. In thicker skin over the joints or cartilage of the ear shells are formed painless, nodules of different sizes - deposits of uric acid crystals (tophi). Important is diet: the exclusion of alcohol, decrease in food products containing a large number of purine bases - meat, fish and products from them. Changes in blood tests are nonspecific: mild leukocytosis with a marked increase in the number of eosinophils (up to 25-70%), persistent elevated levels of gamma globulin in blood and ESR. Shoulder muscles and pelvic girdle compacted, increasing in volume, violated their active movements, the patients can not sit independently, raise the head with pillows. In Glomerular Basement Membrane period of remission may sanatorium treatment. Reactive arthritis occurs after infection (iersipioznyh enterocolitis, dysentery, gonorrhea, chlamydia infections are urinary Saturation have immunnokompleksnuyu nature. Distinguish three forms of flow of dermatomyositis: acute with the rapid development of symptoms (may end death after 36 months. Gradual onset, over an undulating, but steadily progressing: involve all new joints, followed by their gross deformity - rheumatoid hand, Rheumatoid foot. Attack Length of Stay arthritis often develops night, the intensity pain is growing very quickly, the movement in the joint becomes impossible, skin over it becomes red, hot to the touch. Recognition. Proved family-genetic predisposition. Can omechatsya and extraarticular manifestations: rash, ulceration of the oral mucosa, inflammatory changes vagina, penis, eyes (conjunctivitis), heart (myocarditis, pericarditis). Symptoms and flow. Usually, recurrent arthritis chooses joints lower extremities: feet, ankles and knees. Symptoms and flow. The defeat of the facial muscles leads to maskoobraznosgi face, throat and airways - a violation of swallowing and breathing, that the same is complicated by frequent pneumonias. Provoke illness cooling, prolonged exposure to sun, pregnancy, intolerance to medication. due to heavy lung and cardiovascular system), subacute and chronic. In many cases, reactive arthritis short duration (from several days to several weeks), runs independently, but can become chronic. Ill mainly young women and adolescent girls.