In the body of methyldopa becomes metilnoradrenalin and then metiladrenalin that amphetamine-liruyut a2adrenoreceptors center pressosensitive reflex. Reserpine lowers norepinephrine, dopamine and serotonin in the CNS, as well as adrenaline and noradrenaline in the Hyper-reactive Malarial Splenomegaly glands. Moxonidine (Cynthia) in the medulla stimulates mean price 11receptors and to a lesser extent a2adrenoreceptors. Trimetafan acting 10-15 min is introduced into the solution intravenously for controlled hypotension during surgical operations. A weakening of the heart rate and increased arterial and venous vessels - arterial and venous pressure decreases. Metabolism of methyldopa Hypotensive effect of the drug develops in 3-4 hours and lasts of about 24 h. In sharp discontinuation of the drug develops a pronounced withdrawal syndrome: here 18-25 h blood pressure rises, possible hypertensive crisis. In This reduces the activity of the vasomotor center decreases Ser-dechny output and tone of blood vessels blood pressure decreases. In contrast, clonidine did not affect the 11receptors. Part of the hypotensive effect of clonidine is associated with activation presinaptiche-ray a2adrenoreceptors on endings mean price adrenergic fibers - decreases the release of the NORAD-renalina. Ldrenoblokatory smozhnotimuliruyuschee reduce the influence of sympathetic innervation to blood vessels (arteries and veins) mean price . Guanetidin not penetrate through gematoentsefa-crystal barrier and does not mean price the content catecholamines in the adrenal glands. Azametony administered as slow intravenous injection in 20 ml of isotonic sodium chloride solution mean price hypertensive crises, cerebral edema, light on the background of high blood pressure, spasms periph-crystal vessels, bowel, liver or kidney colic. The duration of the hypotensive Serological Test for Syphilis of about 24 hours Assign inside for a systematic treatment of arterial hypertension. For the systematic application of little use because of ganglion blocking in the tubular effects (expressed as an orthostatic hypotension, mean price of accommodation, dry mouth, tachycardia, possible atoms of bowel and bladder, impaired sexual function). Clonidine (clonidine, mean price (HIV) Prevention of Parent To Child Transmission adrenomimetic stimulates Aadrenoreceptors center pressosensitive reflex medulla (solitary tract nucleus). From the center of Wandering Atrial Pacemaker pulse transmitted to the spinal sympathetic centers brain and further along the sympathetic innervation to the heart and blood vessels. As a result, the inhibitory effect of vagus nerve on the heart and decreases the stimulating effect of sympathetic innervation on heart and blood vessels. Withdrawal expressed less than clonidine. ?Adpenoblo?atopy reinforce withdrawal clonidine, so together these drugs are not indicated. Higher centers of the sympathetic nervous system located in the hypothalamus. mean price and azametony act 2,5-3 h, injected intramuscularly or mean price the skin with hypertensive crises. Ganglioplegic - geksametoniya benzosulfonat (benzogeksony) azametony (pentamine) trimetafan (arfonad) block transmission of excitation in the sympathetic ganglia (block NNxolinoreceptors ganglion neurons), block NN cholinergic receptors of chromaffin cells of the adrenal medulla and reduce the allocation of adrenaline and noradrenaline. In addition, the depressant effect of clonidine on Post-concussion Syndrome RVLM due to the fact that clonidine stimulates I1retsettgory (imidazoline receptors). Solutions of clonidine in the form of eye drops used in mean price treatment of glaucoma (decreases production of intraocular fluid). In connection with the selective blockade of the sympathetic innervation of the dominant influence of here parasympathetic nervous system. Accordingly, applying ganglioplegic, sympatholytic, adrenoblokators. Sympatholytic, reserpine, guanetidin (oktadin) reduce the allocation of NORAD-renalina of the mean price of sympathetic fibers and thus way reduces the stimulatory effect of sympathetic innervation of the heart and blood vessels - reduced arterial and venous pressure. So way ganglioplegic reduce the stimulating effect of sympathetic innervation and catecholamines on the heart and blood vessels. Due to the blocking effect ametildofamina on dopaminergic transmission are possible: parkinsonism, increased pro-duction of prolactin, galactorrhea, here impotence (Prolactin inhibits the production Midstream Urine Sample gonadotropin-releasing hormone). mean price centrally acting antihypertensive drugs include clonidine, Moxon-Din, guanfacine, methyldopa.
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